Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30059382 | 0.82 | TSHR (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL2705261 | 0.82 | MGAM (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL472554 | 0.82 | TSHR (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27268424 | 0.81 | MGAM (0.44) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL16411295 | 0.80 | MAPT (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL17962546 | 0.80 | — | — | |
| SCHEMBL27551575 | 0.80 | TSHR (0.48) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL21955400 | 0.79 | MGAM (0.52) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27711401 | 0.79 | MGAM (0.43) | MGAMGAASIMGAM2 | |
| SCHEMBL28755012 | 0.78 | MGAM (0.46) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472411-A | 1,4-Dihydropyridine derivatives and use as vasodilators | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0092936-A1 | 1,4-Dihydropyridine derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1983-11-02 | — | — | EP | disclosed |