Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | MC1R | Q01726 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362639 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BMC4RMC3RMC1R | |
| SCHEMBL7937537 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BMC4RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL7362338 | 0.99 | ITGB3 (0.47) | ITGB3ITGA2BMC4RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL7924926 | 0.99 | ITGB3 (0.47) | ITGB3ITGA2BMC4RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL7362333 | 0.99 | ITGB3 (0.47) | ITGB3ITGA2BMC4RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL7371043 | 0.92 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL7371051 | 0.92 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL7924888 | 0.92 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL7371674 | 0.92 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL7364908 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |