Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474293 | 0.93 | KDM4E (0.56) | CHRM4KDM4EACHEPKMGPR119 | |
| SCHEMBL3779080 | 0.92 | CHRM4 (0.56) | CHRM4KDM4EALDH1A1ACHEPKM | |
| Hydrochloric Acid SCHEMBL3966170 | 0.91 | CHRM4 (0.55) | CHRM4KDM4EALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL3570582 | 0.90 | ACHE (0.61) | CHRM4KDM4EALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL642727 | 0.85 | JAK2 (0.54) | CHRM4KDM4EALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL642728 | 0.85 | JAK2 (0.54) | CHRM4KDM4EALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL9058559 | 0.85 | KMT2A (0.58) | CHRM4KDM4EALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL13443092 | 0.83 | ACHE (0.54) | KDM4EALDH1A1ACHESMN1; SMN2GPR119 | |
| SCHEMBL27648293 | 0.83 | MAPT (0.56) | KDM4EALDH1A1ACHEGPR119MAPT | |
| SCHEMBL23270010 | 0.82 | TP53 (0.53) | CHRM4KDM4EACHEPKMGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |