SCHEMBL7362815

SCHEMBL7362815

Cc1ccsc1C(=CCCN1CCC=C(C(=O)O)C1)c1sccc1C

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 6/20 0.63
PTGS1 P23219 1/20 0.57
PDE4A P27815 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9773388 0.94 SLC6A1 (0.56) SLC6A1PTGS1PDE4A
SCHEMBL9773381 0.94 SLC6A1 (0.56) SLC6A1PTGS1PDE4A
SCHEMBL9773465 0.94 SLC6A1 (0.56) SLC6A1PTGS1PDE4A
SCHEMBL9773368 0.94 SLC6A1 (0.56) SLC6A1PTGS1PDE4A
SCHEMBL8817877 0.93 SLC6A1 (0.72) SLC6A1PTGS1PDE4A
SCHEMBL9773364 0.92 SLC6A1 (0.56) SLC6A1PTGS1PDE4A
SCHEMBL10406288 0.92 SLC6A1 (0.59) SLC6A1PTGS1PDE4A
SCHEMBL9773337 0.91 SLC6A1 (0.53) SLC6A1PTGS1PDE4A
SCHEMBL10407476 0.91 SLC6A1 (0.61) SLC6A1PTGS1PDE4A
SCHEMBL9773487 0.91 SLC6A1 (0.58) SLC6A1PTGS1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0236342-B1 AMINO ACID DERIVATIVES NOVO NORDISK A/S (DK) 1991-09-11 EP disclosed
US-5010090-A N-(butenyl substituted) azaheterocyclic carboxylic acids NOVO NORDISK A/S. (DK) 1991-04-23 US disclosed
EP-0236342-A1 AMINO ACID DERIVATIVES. NOVO INDUSTRI AS (DK) 1987-09-16 EP disclosed
WO-1987000171-A1 AMINO ACID DERIVATIVES NOVO INDUSTRI A/S (DK) 1987-01-15 WO disclosed