Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL15163599 | 0.94 | MAOA (0.38) | MAOAMAOBSMN1; SMN2LMNACRHBP | |
| SCHEMBL29434883 | 0.94 | MAOA (0.41) | MAOAMAOBSMN1; SMN2LMNACRHBP | |
| SCHEMBL1420110 | 0.94 | MAOA (0.41) | MAOAMAOBSMN1; SMN2LMNACRHBP | |
| SCHEMBL7197365 | 0.94 | MAOA (0.41) | MAOAMAOBSMN1; SMN2LMNACRHBP | |
| SCHEMBL9209 | 0.94 | MAOA (0.41) | MAOAMAOBSMN1; SMN2LMNACRHBP | |
| SCHEMBL2143603 | 0.91 | MAOA (0.39) | MAOAMAOBSMN1; SMN2LMNACRHBP | |
| SCHEMBL151338 | 0.91 | MAOA (0.39) | MAOAMAOBSMN1; SMN2LMNACRHBP | |
| SCHEMBL39996 | 0.91 | MAOA (0.39) | MAOAMAOBSMN1; SMN2LMNACRHBP | |
| SCHEMBL887939 | 0.91 | MAOA (0.39) | MAOAMAOBSMN1; SMN2LMNACRHBP | |
| SCHEMBL4860431 | 0.91 | MAOA (0.39) | MAOAMAOBSMN1; SMN2LMNACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028157-A1 | NOVEL PIPERIDINE DERIVATIVES 4-SUBSTITUTED BY AN IMIDAZOLIDIN-2-ON-1-YL-ETHYL, TETRAHYDROPYRIMIDIN-2-ON-1-YL-ETHYL AND 1,3-DIAZEPIN-2-ON-1-YL-ETHYL GROUP, AND USE THEREOF AS α2-ADRENERGIC RECEPTOR ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 1997-08-07 | — | — | WO | claimed |
| JP-3004532-A | — | — | None | — | — | JP | disclosed |
| JP-H034532-A | MANUFACTURE OF COMPOUND SEMICONDUCTOR DEVICE | NIPPON MINING CO LTD | 1991-01-10 | — | — | JP | disclosed |