Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886986 | 0.83 | TSHR (0.37) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL5490241 | 0.82 | MAPT (0.37) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL320015 | 0.80 | — | — | |
| SCHEMBL5484580 | 0.78 | CHRM1 (0.38) | TSHRCHRM1 | |
| SCHEMBL28638213 | 0.78 | — | — | |
| SCHEMBL7159288 | 0.76 | MAPT (0.36) | — | |
| SCHEMBL5490374 | 0.75 | TSHR (0.46) | TSHR | |
| SCHEMBL5699404 | 0.74 | FAAH (0.50) | — | |
| SCHEMBL5493072 | 0.72 | FAAH (0.53) | — | |
| SCHEMBL8940698 | 0.71 | TP53 (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1094730-A | Peptides | SANDOZ LTD (CH) | 1994-11-09 | — | — | CN | disclosed |
| EP-0611375-A1 | PEPTIDES INHIBITING IL-1 BETA RELEASE | SANDOZ LTD. (CH) | 1994-08-24 | — | — | EP | disclosed |
| WO-1993009135-A1 | PEPTIDES INHIBITING IL-1 BETA RELEASE | SANDOZ LTD. (CH) | 1993-05-13 | — | — | WO | disclosed |