Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43677 | 0.88 | KCNA3 (0.58) | KCNA3PKMTHRBHTR1BDRD2 | |
| SCHEMBL13861888 | 0.86 | KCNA3 (0.53) | KCNA3PKMTHRBDRD2DRD4 | |
| SCHEMBL13861891 | 0.86 | KCNA3 (0.53) | KCNA3PKMTHRBDRD2DRD4 | |
| SCHEMBL2481801 | 0.83 | KCNA3 (0.70) | KCNA3PKMHTR1BDRD2DRD4 | |
| SCHEMBL148066 | 0.83 | KCNA3 (0.70) | KCNA3PKMHTR1BDRD2DRD4 | |
| SCHEMBL11087417 | 0.83 | KCNA3 (0.70) | KCNA3PKMHTR1BDRD2DRD4 | |
| SCHEMBL10452423 | 0.83 | KCNA3 (0.70) | KCNA3PKMHTR1BDRD2DRD4 | |
| SCHEMBL5067163 | 0.83 | KCNA3 (0.70) | KCNA3PKMHTR1BDRD2DRD4 | |
| SCHEMBL466750 | 0.83 | KCNA3 (0.70) | KCNA3PKMHTR1BDRD2DRD4 | |
| SCHEMBL96854 | 0.82 | KCNA3 (0.62) | KCNA3PKMHTR1BDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | disclosed |