SCHEMBL43677

SCHEMBL43677

O=CCCOc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.58
TAAR1 Q96RJ0 1/20 0.52
ALDH1A1 P00352 1/20 0.52
RECQL P46063 1/20 0.52
HTR1B P28222 2/20 0.52
DRD4 P21917 2/20 0.52
DRD2 P14416 1/20 0.52
DRD3 P35462 1/20 0.52
HTR1D P28221 1/20 0.52
PKM P14618 2/20 0.48
THRB P10828 1/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL96854 0.89 KCNA3 (0.62) KCNA3TAAR1ALDH1A1RECQLHTR1B
SCHEMBL7363052 0.88 KCNA3 (0.50) KCNA3TAAR1ALDH1A1RECQLHTR1B
SCHEMBL96602 0.87 KCNA3 (0.67) KCNA3TAAR1ALDH1A1RECQLHTR1B
SCHEMBL5593684 0.85 KCNA3 (0.64) KCNA3TAAR1ALDH1A1RECQLHTR1B
SCHEMBL1172269 0.85 KCNA3 (0.64) KCNA3TAAR1ALDH1A1RECQLHTR1B
SCHEMBL96055 0.85 KCNA3 (0.64) KCNA3TAAR1ALDH1A1RECQLHTR1B
SCHEMBL7500091 0.85 KCNA3 (0.64) KCNA3TAAR1ALDH1A1RECQLHTR1B
SCHEMBL9683773 0.85 KCNA3 (0.64) KCNA3TAAR1ALDH1A1RECQLHTR1B
SCHEMBL2786288 0.85 KCNA3 (0.64) KCNA3TAAR1ALDH1A1RECQLHTR1B
SCHEMBL16672084 0.84 MAPK1 (0.42) KCNA3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118222236-A Dispersion adhesives 科思创知识产权两合公司 2024-06-21 CN claimed
CN-117510338-A Natural naphthoquinone derivative and preparation method and application thereof 贵州大学 2024-02-06 CN claimed
CN-116783228-A Storage-stable 1K spray adhesives based on polyurethane dispersions 科思创德国股份有限公司 2023-09-19 CN claimed
CN-112867745-B Dispersion adhesives 科思创知识产权两合公司 2022-11-15 CN claimed
CN-114933620-A Azithromycin derivatives having epithelial barrier enhancing properties 艾比恩多制药有限责任公司 2022-08-23 CN claimed
US-20220106349-A1 Compounds EPIENDO PHARMACEUTICALS EHF (IS) 2022-04-07 US claimed
US-11236120-B2 Azithromycin derivatives with epithelial barrier enhancement properties EPIENDO PHARMACEUTICALS EHF (IS) 2022-02-01 US claimed
CN-112867745-A Dispersion adhesives 科思创知识产权两合公司 2021-05-28 CN claimed
US-20200317710-A1 Azithromycin Derivatives With Epithelial Barrier Enhancement Properties EPIENDO PHARMACEUTICALS EHF (IS) 2020-10-08 US claimed
EP-3708573-A1 AZITHROMYCIN DERIVATIVES WITH EPITHELIAL BARRIER ENHANCEMENT PROPERTIES EpiEndo Pharmaceuticals ehf. (IS) 2020-09-16 EP claimed
US-4900863-A Process for the purification of N-acylaspartame HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-13 US claimed
WO-1989009611-A1 CYCLIC ANALOGS OF ATRIAL NATRIURETIC PEPTIDES CALIFORNIA BIOTECHNOLOGY INC. (US) 1989-10-19 WO claimed
EP-0323740-A2 Linear analogs of atrial natriuretic peptides CALIFORNIA BIOTECHNOLOGY, INC. (US) 1989-07-12 EP claimed
WO-1989005654-A1 LINEAR ANALOGS OF ATRIAL NATRIURETIC PEPTIDES CALIFORNIA BIOTECHNOLOGY INC. (US) 1989-06-29 WO claimed
US-4438136-A INHIBITION OF THROMBOXANE ACTIVITY NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-03-20 US claimed
EP-0013608-B1 SUBSTITUTED BICYCLO (2,2,1)HEPTANES AND HEPT-2-ENES AND THEIR PHARMACEUTICAL COMPOSITIONS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1983-06-15 EP claimed
US-4269773-A CEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1981-05-26 US claimed
EP-0003584-B1 PHENOXYPROPANOIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AG (DE) 1981-01-21 EP claimed
US-4070458-A MICRBIAL ENZYME SANRAKU-OCEAN CO., LTD. (JA) 1978-01-24 US claimed
US-4055468-A TETRAPEPTIDE SANRAKU-OCEAN CO., LTD. (JA) 1977-10-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220106349-A1 Compounds CFTR, AQP1, CTSA KCNA3 1966/4885TAAR1 4878/4885ALDH1A1 1837/4885
US-11236120-B2 Azithromycin derivatives with epithelial barrier enhancement properties CFTR, AQP1, CTSA KCNA3 1973/4885TAAR1 4867/4885ALDH1A1 2483/4885
US-20200317710-A1 Azithromycin Derivatives With Epithelial Barrier Enhancement Properties CFTR, AQP1, CTSA KCNA3 1973/4885TAAR1 4867/4885ALDH1A1 2483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.