Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | HTR6 | P50406 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7364527 | 1.00 | SLC6A4 (0.71) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL7328027 | 0.87 | SLC6A4 (0.63) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| Hydrochloric Acid SCHEMBL9237633 | 0.87 | SLC6A4 (0.63) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL7325315 | 0.84 | SLC6A4 (0.69) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL13323539 | 0.83 | SLC6A4 (1.00) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL4674658 | 0.83 | SLC6A4 (1.00) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| Hydrochloric Acid SCHEMBL11439099 | 0.83 | SLC6A4 (1.00) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL8869768 | 0.82 | SLC6A4 (0.75) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL8870272 | 0.82 | SLC6A4 (0.67) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL7207543 | 0.82 | NOS3 (0.56) | SLC6A4KDM4ELMNAPOLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674620-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | claimed |
| WO-1994014771-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | claimed |
| EP-0674620-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014771-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | disclosed |