Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368660 | 0.84 | F2 (0.62) | F2PRSS1 | |
| SCHEMBL7362821 | 0.81 | F2 (0.73) | F2 | |
| SCHEMBL7372885 | 0.80 | F2 (0.57) | F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7364912 | 0.76 | F2 (0.49) | F2PRSS1 | |
| SCHEMBL7361942 | 0.75 | F2 (0.42) | F2PRSS1 | |
| SCHEMBL7715249 | 0.73 | F2 (0.76) | F2PRSS1 | |
| SCHEMBL7372745 | 0.71 | F2 (0.75) | F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7364412 | 0.67 | F2 (0.49) | F2PRSS1 | |
| SCHEMBL7216987 | 0.67 | F2 (0.63) | F2PRSS1 | |
| SCHEMBL7366746 | 0.66 | SSTR4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259506-A1 | PYRAZINONE THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001038323-A1 | PYRAZINONE THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2001-05-31 | — | — | WO | disclosed |