Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716534 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL14322074 | 0.81 | USP2 (0.44) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL10635756 | 0.80 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL16065593 | 0.78 | KMT2A (0.51) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL18082594 | 0.78 | KMT2A (0.39) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL18082602 | 0.78 | KMT2A (0.39) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL23501579 | 0.77 | KMT2A (0.41) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL18269631 | 0.77 | USP2 (0.40) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL18082592 | 0.77 | KMT2A (0.41) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL18082591 | 0.77 | KMT2A (0.41) | USP2SMN1; SMN2HPGDTP53ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112269-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015634-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |