Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363294 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19NPC1RAB9ADPP4 | |
| SCHEMBL8790576 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2C19NPC1RAB9AKCNH2 | |
| SCHEMBL8790586 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2C19NPC1RAB9AKCNH2 | |
| SCHEMBL8790582 | 0.82 | CYP2C19 (0.41) | SMN1; SMN2CYP2C19DPP4KCNH2DPP7 | |
| SCHEMBL8790127 | 0.82 | CYP2C19 (0.41) | SMN1; SMN2CYP2C19DPP4KCNH2DPP7 | |
| SCHEMBL10853040 | 0.81 | ALDH1A1 (0.49) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL8791458 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19NPC1RAB9APOLB | |
| SCHEMBL20612426 | 0.80 | MEN1 (0.58) | SMN1; SMN2CYP2C19NPC1RAB9ADPP4 | |
| SCHEMBL16465286 | 0.80 | MEN1 (0.58) | SMN1; SMN2CYP2C19NPC1RAB9ADPP4 | |
| SCHEMBL16466450 | 0.80 | MEN1 (0.58) | SMN1; SMN2CYP2C19NPC1RAB9ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020172-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1996-07-04 | — | — | WO | disclosed |