SCHEMBL7363389

SCHEMBL7363389

O=C(O)C(O)CNC(=O)C(Cc1ccccc1)CP(=O)(O)O

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.49
CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7367028 0.89 FOLH1 (0.55) FOLH1CYP1A2
SCHEMBL7440491 0.85 FOLH1 (0.51) FOLH1CYP1A2
SCHEMBL7364484 0.85 ANPEP (0.50) FOLH1
SCHEMBL10790731 0.84 ANPEP (0.49) FOLH1
SCHEMBL10790739 0.84 ANPEP (0.49) FOLH1
SCHEMBL7366135 0.84 FOLH1 (0.47) FOLH1CYP1A2
SCHEMBL9516943 0.83 MME (0.67) FOLH1
SCHEMBL7361616 0.82 FOLH1 (0.48) FOLH1CYP1A2
SCHEMBL7363272 0.82 FOLH1 (0.45) FOLH1
SCHEMBL7366614 0.81 ANPEP (0.46) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0117429-B1 PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES SCHERING CORPORATION (US) 1987-09-02 EP claimed
EP-0117429-A1 Phosphorous containing compounds as inhibitors of enkephalinases SCHERING CORPORATION (US) 1984-09-05 EP claimed
EP-0117429-B1 PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES SCHERING CORPORATION (US) 1987-09-02 EP disclosed
EP-0117429-A1 Phosphorous containing compounds as inhibitors of enkephalinases SCHERING CORPORATION (US) 1984-09-05 EP disclosed