Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790739 | 0.99 | ANPEP (0.49) | ANPEPERAP2FOLH1 | |
| SCHEMBL10790731 | 0.99 | ANPEP (0.49) | ANPEPERAP2FOLH1 | |
| SCHEMBL7364582 | 0.92 | MME (0.57) | ANPEP | |
| SCHEMBL10790734 | 0.90 | ANPEP (0.46) | ANPEPERAP2 | |
| SCHEMBL7364462 | 0.90 | EPHX2 (0.48) | ANPEP | |
| SCHEMBL10790065 | 0.88 | MME (0.42) | ANPEP | |
| SCHEMBL7367028 | 0.87 | FOLH1 (0.55) | ANPEPERAP2FOLH1 | |
| SCHEMBL7363389 | 0.85 | FOLH1 (0.49) | FOLH1 | |
| SCHEMBL7440491 | 0.84 | FOLH1 (0.51) | ANPEPERAP2FOLH1 | |
| SCHEMBL7363272 | 0.83 | FOLH1 (0.45) | ANPEPERAP2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |