Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Carbamate SCHEMBL28630699 | 0.88 | ALDH1A1 (0.53) | ALDH1A1SYKMAPK1L3MBTL1LMNA | |
| Benzyl Carbamate SCHEMBL10864834 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL8916141 | 0.81 | MEN1 (0.56) | ALDH1A1L3MBTL1KMT2AGAARAB9A | |
| Benzyl Carbamate SCHEMBL6992838 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| Benzyl Carbamate SCHEMBL8592590 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| Benzyl Carbamate SCHEMBL10700633 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| Benzyl Carbamate SCHEMBL30227887 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| Benzyl Carbamate SCHEMBL1697 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| Benzyl Carbamate SCHEMBL30227819 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| Benzyl Carbamate SCHEMBL28086051 | 0.79 | ALDH1A1 (0.62) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348953-A | Elastase inhibitor | MERCK & CO., INC. (US) | 1994-09-20 | — | — | US | disclosed |
| WO-1994013636-A1 | NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | disclosed |
| EP-0525973-A2 | Substituted azetidinones as anti-inflammatory and antidegenerative agents | MERCK & CO. INC. (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1993000332-A1 | SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1993-01-07 | — | — | WO | disclosed |