Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.69 |
| ▸ | PDE4A | P27815 | 19/20 | 0.69 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371833 | 1.00 | PDE4B (0.69) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7356382 | 0.92 | PDE4A (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7356387 | 0.92 | PDE4A (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7363837 | 0.92 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8472314 | 0.92 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8330022 | 0.90 | PDE4A (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7404561 | 0.90 | PDE4A (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8330028 | 0.90 | PDE4A (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6172674 | 0.89 | PDE4A (0.52) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6172676 | 0.89 | PDE4A (0.52) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869677-A | 3,3-(disubstituted)cyclohexan-1-carboxylate monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-02-09 | — | — | US | claimed |
| US-5990119-A | 1,4,4-(trisubstituted)cyclohexane monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-23 | — | — | US | disclosed |
| US-5869677-A | 3,3-(disubstituted)cyclohexan-1-carboxylate monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-02-09 | — | — | US | disclosed |
| US-5863926-A | 4,4-(disubstituted)cyclohexan-1-carboxylate monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-26 | — | — | US | disclosed |
| EP-0796096-A4 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-CARBOXYLATE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0796097-A4 | 3,3-(DISUBSTITUTED)CYCLOHEXAN-1-CARBOXYLATE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-03-25 | — | — | EP | disclosed |
| EP-0796096-A1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-CARBOXYLATE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-24 | — | — | EP | disclosed |
| EP-0796097-A1 | 3,3-(DISUBSTITUTED)CYCLOHEXAN-1-CARBOXYLATE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996019994-A1 | 3,3-(DISUBSTITUTED)CYCLOHEXAN-1-CARBOXYLATE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |
| WO-1996019990-A1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-CARBOXYLATE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |