Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.55 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759218 | 0.83 | CTSS (0.61) | CTSSCTSLCTSKREN | |
| SCHEMBL5757363 | 0.77 | CTSS (0.61) | CTSSCTSL | |
| SCHEMBL5758603 | 0.77 | CTSS (0.61) | CTSSCTSL | |
| SCHEMBL5757358 | 0.77 | CTSS (0.61) | CTSSCTSL | |
| SCHEMBL5760517 | 0.74 | CTSS (0.77) | CTSSCTSLCTSKREN | |
| SCHEMBL5758379 | 0.73 | CTSS (0.66) | CTSSCTSLCTSK | |
| SCHEMBL5756972 | 0.73 | CTSS (0.73) | CTSSCTSLCTSKREN | |
| SCHEMBL5760506 | 0.72 | CTSS (0.76) | CTSSCTSLCTSKREN | |
| SCHEMBL5761262 | 0.71 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5758384 | 0.69 | CTSS (1.00) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204652-A1 | NOVEL SUCCINATE DERIVATIVE COMPOUNDS USEFUL AS CYSTEINE PROTEASE INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009110-A1 | NOVEL SUCCINATE DERIVATIVE COMPOUNDS USEFUL AS CYSTEINE PROTEASE INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-02-08 | — | — | WO | disclosed |