Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651670 | 0.87 | LOXL2 (0.60) | LOXL2HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6651863 | 0.87 | LOXL2 (0.60) | LOXL2HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6651861 | 0.87 | LOXL2 (0.60) | LOXL2HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2839532 | 0.83 | LOXL2 (0.64) | LOXL2HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6632792 | 0.83 | LOXL2 (0.56) | LOXL2HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8323672 | 0.82 | LOXL2 (0.58) | LOXL2HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8319172 | 0.82 | LOXL2 (0.62) | LOXL2HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7730593 | 0.80 | AAK1 (0.49) | LOXL2HPGDCYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL6356550 | 0.79 | HPGD (0.52) | LOXL2HPGDCYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL7347434 | 0.79 | HPGD (0.52) | LOXL2HPGDCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |