Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 3/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CCKAR | P32238 | 2/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7357517 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BITGA2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7362872 | 0.98 | ITGB3 (0.43) | ITGB3ITGA2BITGA2MEN1KMT2A | |
| SCHEMBL7358065 | 0.96 | ITGB3 (0.37) | ITGB3ITGA2BITGA2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7354484 | 0.93 | ITGB3 (0.46) | ITGB3ITGA2BITGA2MPOMMP13 | |
| Trifluoroacetic Acid SCHEMBL7356213 | 0.91 | ITGB3 (0.44) | ITGB3ITGA2BITGA2MMP13HDAC3 | |
| SCHEMBL7357668 | 0.91 | KDM4E (0.41) | ITGB3ITGA2BITGA2CCKBRTPSAB1 | |
| SCHEMBL7357523 | 0.90 | MEN1 (0.35) | ITGB3ITGA2BITGA2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL8842940 | 0.88 | ATM (0.41) | ITGB3ITGA2BHDAC1HDAC8 | |
| SCHEMBL7356598 | 0.87 | ITGB3 (0.36) | ITGB3ITGA2BMMP13HRH2HDAC3 | |
| Trifluoroacetic Acid SCHEMBL7356143 | 0.87 | ITGB3 (0.39) | ITGB3ITGA2BITGA2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5565449-A | PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| US-5250679-A | Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor | GENENTECH, INC. (US) | 1993-10-05 | — | — | US | disclosed |
| WO-1993008174-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR | GENENTECH, INC. (US) | 1993-04-29 | — | — | WO | disclosed |