Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 6/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 7/20 | 0.46 |
| ▸ | TLR4 | O00206 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABL2 | P42684 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364026 | 1.00 | VCP (0.49) | VCPEGFRSYKALDH1A1MAPT | |
| SCHEMBL13677650 | 0.84 | VCP (0.52) | VCPEGFRSYKALDH1A1MAPT | |
| SCHEMBL7390829 | 0.82 | VCP (0.70) | VCPEGFRSYKALDH1A1MAPT | |
| SCHEMBL7361007 | 0.82 | VCP (0.70) | VCPEGFRSYKALDH1A1MAPT | |
| SCHEMBL7355608 | 0.82 | VCP (0.70) | VCPEGFRSYKALDH1A1MAPT | |
| SCHEMBL4891193 | 0.82 | VCP (0.70) | VCPEGFRSYKALDH1A1MAPT | |
| SCHEMBL7358653 | 0.81 | VCP (0.49) | VCPEGFRSYKALDH1A1MAPT | |
| SCHEMBL7398936 | 0.81 | VCP (0.52) | VCPEGFRSYKALDH1A1MAPT | |
| SCHEMBL7358656 | 0.81 | VCP (0.49) | VCPEGFRSYKALDH1A1MAPT | |
| SCHEMBL7398937 | 0.81 | VCP (0.52) | VCPEGFRSYKALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538384-A4 | OXAMIDES | SMITHKLINE BEECHAM CORP (US) | 1995-04-12 | — | — | EP | disclosed |
| US-5393788-A | Phenylalkyl oxamides | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0538384-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000968-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |