Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17473821 | 0.82 | KMT2A (0.41) | MEN1KMT2AALDH1A1HPGDUSP2 | |
| SCHEMBL11131843 | 0.78 | HSPA5 (0.58) | MEN1KMT2ATDP1TSHRMAPT | |
| SCHEMBL17063499 | 0.78 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1HPGDTDP1 | |
| SCHEMBL6912345 | 0.78 | GAA (0.41) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL28131039 | 0.78 | TAAR1 (0.45) | MEN1KMT2AALDH1A1HPGDUSP2 | |
| SCHEMBL1404275 | 0.77 | CHRM2 (0.46) | MEN1KMT2AALDH1A1HPGDUSP2 | |
| SCHEMBL30038773 | 0.75 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1HPGDUSP2 | |
| SCHEMBL8627679 | 0.75 | NPSR1 (0.48) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL28546393 | 0.75 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1HPGDUSP2 | |
| SCHEMBL27593168 | 0.74 | SLC6A2 (0.40) | KMT2AALDH1A1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087937-A1 | CYCLIC HYDROXAMIC ACIDS AS METALLOPROTEINASE INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065867-A1 | CYCLIC HYDROXAMIC ACIDS AS METALLOPROTEINASE INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |