Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | CDK4 | P11802 | 7/20 | 0.52 |
| ▸ | CCND1 | P24385 | 7/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368298 | 0.78 | ITGB3 (0.59) | — | |
| SCHEMBL8359098 | 0.76 | ITGB3 (0.69) | — | |
| SCHEMBL7329136 | 0.76 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL4331421 | 0.71 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL7866515 | 0.69 | MEN1 (0.73) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL14303574 | 0.69 | MEN1 (0.90) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL12194964 | 0.69 | NPC1 (0.74) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL14198238 | 0.69 | CDK4 (0.77) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL13376826 | 0.68 | NPC1 (0.54) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL15047821 | 0.68 | MEN1 (0.82) | MEN1KMT2ANPC1RAB9ACDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | claimed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | claimed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | claimed |