Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.40 |
| ▸ | PER2 | O15055 | 1/20 | 0.40 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.40 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255195 | 0.85 | CACNA1H (0.43) | CACNA1HKCNH2FFAR4FFAR1PER2 | |
| SCHEMBL8157650 | 0.73 | BRD4 (0.50) | CACNA1HKCNH2FFAR4FFAR1PER2 | |
| SCHEMBL19673967 | 0.73 | FFAR4 (0.44) | CACNA1HKCNH2FFAR4FFAR1PER2 | |
| SCHEMBL9754343 | 0.73 | CACNA1H (0.47) | CACNA1HKCNH2FFAR4FFAR1PER2 | |
| SCHEMBL7850153 | 0.72 | ATM (0.57) | CACNA1HKCNH2FFAR4FFAR1PER2 | |
| SCHEMBL3587960 | 0.70 | FFAR4 (0.42) | CACNA1HKCNH2FFAR4FFAR1PER2 | |
| SCHEMBL8242189 | 0.70 | PER2 (0.51) | CACNA1HKCNH2FFAR4FFAR1PER2 | |
| SCHEMBL28194834 | 0.69 | FFAR4 (0.44) | CACNA1HKCNH2FFAR4FFAR1PER2 | |
| SCHEMBL28207011 | 0.69 | FFAR4 (0.44) | CACNA1HKCNH2FFAR4FFAR1PER2 | |
| SCHEMBL10278293 | 0.69 | PER2 (0.50) | CACNA1HKCNH2FFAR4FFAR1PER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175419-A2 | ARYL SULFONYLS AS FACTOR XA INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000059902-A2 | ARYL SULFONYLS AS FACTOR XA INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |