Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561385 | 0.84 | ALDH1A1 (0.63) | ALDH1A1NPSR1NPC1HTTRAB9A | |
| SCHEMBL5873285 | 0.84 | ALDH1A1 (0.52) | ALDH1A1NPSR1NPC1HTTRAB9A | |
| SCHEMBL28390011 | 0.81 | ALDH1A1 (0.48) | ALDH1A1NPSR1NPC1HTTRAB9A | |
| SCHEMBL10490218 | 0.81 | ALDH1A1 (0.70) | ALDH1A1NPSR1NPC1HTTRAB9A | |
| SCHEMBL3388559 | 0.81 | ALDH1A1 (0.48) | ALDH1A1NPSR1NPC1HTTRAB9A | |
| SCHEMBL9190721 | 0.81 | ALDH1A1 (0.48) | ALDH1A1NPSR1NPC1HTTRAB9A | |
| SCHEMBL6768372 | 0.81 | ALDH1A1 (0.48) | ALDH1A1NPSR1NPC1HTTRAB9A | |
| SCHEMBL15667384 | 0.80 | ALDH1A1 (0.47) | ALDH1A1NPSR1NPC1HTTRAB9A | |
| SCHEMBL8954554 | 0.79 | NPSR1 (0.47) | ALDH1A1NPSR1NPC1HTTRAB9A | |
| SCHEMBL109362 | 0.79 | ALDH1A1 (0.47) | ALDH1A1NPSR1NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290848-A | Super excellent oxidative catalyst based on macrocyclic compound | 卡内基美浓大学 | 2018-07-17 | — | — | CN | disclosed |
| CN-1264821-C | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SUNTORY LTD (JP) | 2006-07-19 | — | — | CN | disclosed |
| EP-0942924-A2 | METHODS AND COMPOUNDS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | Elan Pharmaceuticals, Inc. (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |
| WO-1998022494-A2 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1998-05-28 | — | — | WO | disclosed |
| CN-1025620-C | Process for the preparation of 1-carba (dethia) cephalosporins | LILLY CO ELI (US) | 1994-08-10 | — | — | CN | disclosed |
| CN-1041593-A | The preparation method of 1-kappa (dethia) cynnematin | LILLY CO ELI (US) | 1990-04-25 | — | — | CN | disclosed |