Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 11/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329220 | 0.84 | SLC2A1 (0.45) | — | |
| SCHEMBL6555102 | 0.74 | TDP1 (0.46) | CETPNPC1RAB9A | |
| SCHEMBL7400975 | 0.73 | HDAC1 (0.44) | ITGB3ITGA2B | |
| SCHEMBL9023827 | 0.72 | LSS (0.48) | KMT2AITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8838086 | 0.71 | TRPV1 (0.44) | HTR1ADRD2ITGB3ITGA2B | |
| SCHEMBL27443430 | 0.71 | AOC3 (0.48) | HTR1ADRD2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8838061 | 0.70 | HRH3 (0.53) | MEN1KMT2ADRD2 | |
| SCHEMBL9100936 | 0.70 | SMN1; SMN2 (0.48) | RAB9AMEN1KMT2A | |
| SCHEMBL7501490 | 0.69 | DRD2 (0.56) | HTR1ADRD2 | |
| SCHEMBL7329223 | 0.68 | KHK (0.44) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022834-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |