Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 14/20 | 0.60 |
| ▸ | GNPAT | O15228 | 1/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831556 | 0.84 | NOD1 (0.75) | NOD1GNPATSLC6A5HDAC2 | |
| SCHEMBL9831553 | 0.84 | NOD1 (0.75) | NOD1GNPATSLC6A5HDAC2 | |
| SCHEMBL31039943 | 0.84 | NOD1 (0.70) | NOD1GNPATSLC6A5HDAC2 | |
| SCHEMBL8620771 | 0.84 | NOD1 (0.75) | NOD1SLC6A5 | |
| SCHEMBL4398199 | 0.84 | NOD1 (0.75) | NOD1SLC6A5 | |
| SCHEMBL5496148 | 0.84 | NOD1 (0.75) | NOD1SLC6A5 | |
| SCHEMBL29617648 | 0.83 | NOD1 (0.51) | NOD1GNPAT | |
| Selenium SCHEMBL4401992 | 0.83 | NOD1 (0.73) | NOD1SLC6A5 | |
| SCHEMBL28321635 | 0.83 | NOD1 (0.73) | NOD1SLC6A5 | |
| SCHEMBL7170497 | 0.83 | NOD1 (0.84) | NOD1SLC6A5HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414132-A | Peptide intermediates | ZENECA INC. (US) | 1995-05-09 | — | — | US | disclosed |
| US-5194588-A | Inhibitors of human leukocyte elastase, di-, tri- and tetra-peptides | ICI AMERICAS INC. (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0189305-B1 | PEPTIDE DERIVATIVES | ICI AMERICAS INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5055450-A | Di-, tri- and tetrapeptides as inhibitors of human leukocyte elastase | ICI AMERICAS INC. (US) | 1991-10-08 | — | — | US | disclosed |
| US-4910190-A | Containing a nitrogen containing heterocycle ring structure | ICI AMERICAS INC. (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0189305-A2 | Peptide derivatives | ICI AMERICAS INC. (US) | 1986-07-30 | — | — | EP | disclosed |