Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3332959 | 0.81 | TBXA2R (0.33) | CA2TMEM97SIGMAR1TBXA2RTBXAS1 | |
| SCHEMBL3332632 | 0.81 | TBXA2R (0.33) | CA2TMEM97SIGMAR1TBXA2RTBXAS1 | |
| SCHEMBL3332627 | 0.81 | TBXA2R (0.33) | CA2TMEM97SIGMAR1TBXA2RTBXAS1 | |
| SCHEMBL3465825 | 0.81 | UGT2B7 (0.34) | CA2TMEM97SIGMAR1TBXA2RTBXAS1 | |
| SCHEMBL10201598 | 0.79 | HCRTR2 (0.34) | CA2HCRTR2 | |
| SCHEMBL1222860 | 0.79 | CA2 (0.34) | CA2 | |
| SCHEMBL1946817 | 0.79 | CA2 (0.34) | CA2 | |
| SCHEMBL1944725 | 0.79 | CA2 (0.34) | CA2 | |
| SCHEMBL1222856 | 0.79 | CA2 (0.34) | CA2 | |
| SCHEMBL1946172 | 0.79 | CA2 (0.34) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611375-A1 | PEPTIDES INHIBITING IL-1 BETA RELEASE | SANDOZ LTD. (CH) | 1994-08-24 | — | — | EP | disclosed |
| WO-1993009135-A1 | PEPTIDES INHIBITING IL-1 BETA RELEASE | SANDOZ LTD. (CH) | 1993-05-13 | — | — | WO | disclosed |