Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.57 |
| ▸ | F2 | P00734 | 3/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908041 | 0.95 | F10 (0.53) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8443278 | 0.91 | F10 (0.52) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8909375 | 0.91 | F10 (0.53) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8438856 | 0.90 | F10 (0.49) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8909337 | 0.90 | F10 (0.51) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8907806 | 0.89 | F10 (0.50) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8441533 | 0.87 | F10 (0.64) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8604900 | 0.86 | F10 (0.53) | F10F2 | |
| SCHEMBL8438863 | 0.86 | F10 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7366139 | 0.85 | F10 (0.53) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848708-A1 | N,N-DI(ARYLMETHYL)CYCLIC UREA DERIVATIVES AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1998-06-24 | — | — | EP | claimed |
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | claimed |
| WO-1996038421-A1 | N,N-DI(ARYLMETHYL)CYCLIC UREA DERIVATIVES AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1996-12-05 | — | — | WO | claimed |
| EP-0848708-A1 | N,N-DI(ARYLMETHYL)CYCLIC UREA DERIVATIVES AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5731308-A | N,N-di(aryl) cyclic urea derivatives as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-03-24 | — | — | US | disclosed |
| US-5731311-A | N,N-di(aryl) cyclic urea derivatives as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-03-24 | — | — | US | disclosed |
| US-5726173-A | ANTICOAGULANTS | BERLEX LABORATORIES, INC. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1996038421-A1 | N,N-DI(ARYLMETHYL)CYCLIC UREA DERIVATIVES AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1996-12-05 | — | — | WO | disclosed |