Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364511 | 0.90 | F10 (0.57) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8908041 | 0.85 | F10 (0.53) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8443278 | 0.84 | F10 (0.52) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8907806 | 0.82 | F10 (0.50) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8909375 | 0.81 | F10 (0.53) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8438856 | 0.80 | F10 (0.49) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8604900 | 0.80 | F10 (0.53) | F10F2 | |
| SCHEMBL8438863 | 0.79 | F10 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8441533 | 0.78 | F10 (0.64) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8907770 | 0.78 | CFTR (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | claimed |
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | disclosed |