Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845122 | 0.82 | CSNK2A1 (0.56) | CSNK2A1KDM4EATMNUDT1BACE1 | |
| SCHEMBL9587342 | 0.81 | CSNK2A1 (0.55) | CSNK2A1KDM4EATMNUDT1BACE1 | |
| SCHEMBL21255817 | 0.80 | KDM4E (0.66) | CSNK2A1KDM4EATMTAAR1TSHR | |
| SCHEMBL7353001 | 0.80 | KDM4E (0.66) | CSNK2A1KDM4EATMTAAR1TSHR | |
| SCHEMBL20190365 | 0.80 | CSNK2A1 (0.50) | CSNK2A1KDM4EATMNUDT1BACE1 | |
| SCHEMBL9845095 | 0.79 | CSNK2A1 (0.53) | CSNK2A1KDM4EATMNUDT1BACE1 | |
| Hydrochloric Acid SCHEMBL7355268 | 0.79 | KDM4E (0.64) | CSNK2A1KDM4EATMTAAR1TSHR | |
| SCHEMBL7366230 | 0.79 | MEN1 (0.45) | PDE4BRECQLPDE4AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL20188074 | 0.78 | CSNK2A1 (0.51) | CSNK2A1KDM4EATMNUDT1BACE1 | |
| SCHEMBL9845094 | 0.76 | KDM4E (0.53) | CSNK2A1KDM4EATMNUDT1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538384-A4 | OXAMIDES | SMITHKLINE BEECHAM CORP (US) | 1995-04-12 | — | — | EP | disclosed |
| US-5393788-A | Phenylalkyl oxamides | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0538384-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000968-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |