Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.55 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845122 | 0.98 | CSNK2A1 (0.56) | CSNK2A1NUDT1BACE1KDM4EATM | |
| SCHEMBL9845095 | 0.95 | CSNK2A1 (0.53) | CSNK2A1NUDT1BACE1KDM4EATM | |
| SCHEMBL9845094 | 0.92 | KDM4E (0.53) | CSNK2A1NUDT1BACE1KDM4EATM | |
| SCHEMBL21255817 | 0.89 | KDM4E (0.66) | CSNK2A1KDM4EATMPDE4BRECQL | |
| SCHEMBL7353001 | 0.89 | KDM4E (0.66) | CSNK2A1KDM4EATMPDE4BRECQL | |
| Hydrochloric Acid SCHEMBL7355268 | 0.88 | KDM4E (0.64) | CSNK2A1KDM4EATMPDE4BRECQL | |
| SCHEMBL20190365 | 0.86 | CSNK2A1 (0.50) | CSNK2A1NUDT1BACE1KDM4EATM | |
| Hydrochloric Acid SCHEMBL20188074 | 0.84 | CSNK2A1 (0.51) | CSNK2A1NUDT1BACE1KDM4EATM | |
| SCHEMBL7364533 | 0.81 | CSNK2A1 (0.46) | CSNK2A1NUDT1BACE1KDM4EATM | |
| SCHEMBL7324772 | 0.81 | PDE4B (0.55) | CSNK2A1KDM4EATMPDE4BRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246949-A | And lactic acid esters, treatment of hypotension and cardiac circulatory insufficiency | SANSHO CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0431942-A2 | Percutaneously absorbable pharmaceutical preparation containing dopamine derivative | SANSHO CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |