Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368682 | 0.88 | TSHR (0.45) | APEX1ALDH1A1POLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7361883 | 0.87 | TSHR (0.45) | APEX1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL7390175 | 0.85 | APEX1 (0.47) | APEX1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL7360990 | 0.82 | MEN1 (0.39) | APEX1ALDH1A1KMT2AMEN1NOD2 | |
| SCHEMBL7386573 | 0.78 | TSHR (0.47) | APEX1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL7391615 | 0.78 | APEX1 (0.46) | APEX1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL7385435 | 0.78 | DRD2 (0.55) | APEX1ALDH1A1TSHRMAPK10LMNA | |
| SCHEMBL7362850 | 0.77 | PPARA (0.44) | LMNA | |
| SCHEMBL7564483 | 0.77 | APEX1 (0.43) | APEX1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL7564471 | 0.77 | APEX1 (0.43) | APEX1ALDH1A1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |