SCHEMBL7364598

SCHEMBL7364598

Cc1ccc(C(=O)C=CN(C)C)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.70
LMNA P02545 7/20 0.70
RAB9A P51151 5/20 0.70
HPGD P15428 4/20 0.70
CYP1A2 P05177 2/20 0.70
CYP2C19 P33261 2/20 0.70
RECQL P46063 2/20 0.70
ALOX12 P18054 1/20 0.70
ALDH1A1 P00352 10/20 0.69
HTT P42858 5/20 0.69
SMN1; SMN2 Q16637 4/20 0.69
NPSR1 Q6W5P4 3/20 0.69
KMT2A Q03164 3/20 0.69
PKM P14618 2/20 0.69
ATM Q13315 2/20 0.69
MEN1 O00255 2/20 0.69
NLRP1 Q9C000 1/20 0.69
NTSR1 P30989 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
POLB P06746 4/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29176328 1.00 MAPT (0.70) MAPTLMNARAB9AHPGDCYP1A2
SCHEMBL801273 1.00 MAPT (0.70) MAPTLMNARAB9AHPGDCYP1A2
SCHEMBL23251385 0.92 MAPT (0.81) MAPTLMNARAB9AHPGDCYP1A2
SCHEMBL1186588 0.84 MAPT (0.70) MAPTLMNARAB9AHPGDCYP1A2
SCHEMBL1186589 0.84 MAPT (0.70) MAPTLMNARAB9AHPGDCYP1A2
SCHEMBL4894896 0.84 RECQL (0.75) MAPTLMNARAB9AHPGDCYP1A2
SCHEMBL12914243 0.84 MAPT (0.70) MAPTLMNARAB9AHPGDCYP1A2
SCHEMBL4894903 0.84 RECQL (0.75) MAPTLMNARAB9AHPGDCYP1A2
SCHEMBL28984937 0.83 ALDH1A1 (1.00) MAPTLMNARAB9AHPGDALOX12
SCHEMBL14745637 0.82 MAPT (0.68) MAPTLMNARAB9AHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119900035-A Method for synthesizing 2, 5-disubstituted furan by C-C double bond cleavage free radical tandem electricity 南京工业大学 2025-04-29 CN disclosed
CN-115874201-B Electrosynthesis method of furanquinone 南京工业大学 2025-02-25 CN disclosed
CN-119330879-A Synthesis method of quinoline compound 江南大学 2025-01-21 CN disclosed
CN-116240560-A Method for electrochemically synthesizing furoquinone by utilizing microchannel reactor 南京工业大学 2023-06-09 CN disclosed
CN-115874201-A Electric synthesis method of furan quinone 南京工业大学 2023-03-31 CN disclosed
EP-2928471-A1 HISTONE DEMETHYLASE INHIBITORS Quanticel Pharmaceuticals Inc (US) 2015-10-14 EP disclosed
WO-2014089364-A1 HISTONE DEMETHYLASE INHIBITORS QUANTICEL PHARMACEUTICALS, INC (US) 2014-06-12 WO disclosed
US-5977075-A N-aroylamino acid amides as endothelin inhibitors NOVARTIS AG (CH) 1999-11-02 US disclosed
EP-0821670-A1 N-AROYLAMINO ACID AMIDES AS ENDOTHELIN INHIBITORS Novartis AG (CH) 1998-02-04 EP disclosed
US-5703106-A TREATING VARIOUS CARDIOVASCULAR, UROGENITAL, BRAIN DISORDERS JAPAT LTD. (CH) 1997-12-30 US disclosed
WO-1997011960-A1 ANTAGONISTS OF ENDOTHELIN RECEPTORS JAPAT LTD. (CH) 1997-04-03 WO disclosed
EP-0753004-A1 ANTAGONISTS OF ENDOTHELIN RECEPTORS Japat Ltd (CH) 1997-01-15 EP disclosed
WO-1996033170-A1 N-AROYLAMINO ACID AMIDES AS ENDOTHELIN INHIBITORS NOVARITS AG (CH) 1996-10-24 WO disclosed
WO-1995026360-A1 ANTAGONISTS OF ENDOTHELIN RECEPTORS JAPAT LTD. (CH) 1995-10-05 WO disclosed
US-4904658-A Substituted-6H,8H-pyrimido-[1,2,3-cd]purine-8,10-(9H)-diones and substituted-6H,10H-pyrimido[1,2-cd]purin-10-ones AMERICAN CYANAMID COMPANY (US) 1990-02-27 US disclosed
US-4888345-A HYPOTENSIVE AND ANXIOLYTIC AGENTS; CHEMICAL INTERMEDIATES AMERICAN CYANAMID COMPANY (US) 1989-12-19 US disclosed