SCHEMBL7364818

SCHEMBL7364818

O=Cc1ccc(OCCCCCCCCOc2ccc(C=O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
SMN1; SMN2 Q16637 3/20 0.67
MAPT P10636 2/20 0.67
HPGD P15428 2/20 0.67
LMNA P02545 2/20 0.67
KDM4E B2RXH2 2/20 0.53
CYP2A6 P11509 1/20 0.52
KMT2A Q03164 1/20 0.50
GAA P10253 1/20 0.48
RAB9A P51151 1/20 0.47
PPARA Q07869 1/20 0.47
ALDH1A3 P47895 1/20 0.47
ALB P02768 1/20 0.46
KCNA3 P22001 1/20 0.46
STS P08842 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
APP P05067 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3696420 1.00 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL8205008 1.00 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL8192951 1.00 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL8549614 1.00 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL8374769 1.00 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL8373486 1.00 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL8315263 1.00 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL8373505 1.00 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL3113016 1.00 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL8551794 0.98 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2MAPTHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6037447-A DIMERS OF DESHYDROVANCOMYCIN AND/OR DESHYDROA82846B COVALENTLY LINKED THROUGH THEIR DISACCHARIDE AMINE BY LINKER; FOR ANTIBIOTICS/BACTERICIDES ESPECIALLY FOR CONTROL OF GRAM POSITIVE BACTERIA SUCH AS VANCOMYCIN RESISTANT ENTEROCOCCI ELI LILLY AND COMPANY (US) 2000-03-14 US disclosed
EP-0802199-B1 Covalently bound dimers of glycopeptide antibiotics LILLY CO ELI (US) 1999-12-08 EP disclosed
EP-0801075-B1 Covalently linked dimers of glycopeptide antibiotics LILLY CO ELI (US) 1999-07-07 EP disclosed
EP-0696585-B1 NOVEL BISOXADIAZOLIDINE DERIVATIVE YAMANOUCHI PHARMA CO LTD (JP) 1998-12-16 EP disclosed
WO-1997038706-A1 GLYCOPEPTIDE COMPOUNDS ELI LILLY AND COMPANY (US) 1997-10-23 WO disclosed
EP-0802199-A2 Covalently bound dimers of glycopetide antibiotics ELI LILLY AND COMPANY (US) 1997-10-22 EP disclosed
EP-0801075-A1 Covalently linked dimers of glycopeptide antibiotics ELI LILLY AND COMPANY (US) 1997-10-15 EP disclosed
US-5643931-A ANTIDIABETIC AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1997-07-01 US disclosed
EP-0696585-A1 NOVEL BISOXADIAZOLIDINE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1996-02-14 EP disclosed