Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.46 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442396 | 1.00 | FFAR1 (0.51) | FFAR1LTA4HSRD5A2PLAAT3PLAAT5 | |
| SCHEMBL7369384 | 0.98 | FFAR1 (0.53) | FFAR1LTA4HSRD5A2PLAAT3PLAAT5 | |
| SCHEMBL5380612 | 0.92 | FFAR1 (0.55) | FFAR1LTA4HSRD5A2PLAAT3PLAAT5 | |
| SCHEMBL19322273 | 0.90 | FFAR1 (0.60) | FFAR1LTA4HSRD5A2PLAAT3PLAAT5 | |
| SCHEMBL19322285 | 0.90 | FFAR1 (0.60) | FFAR1LTA4HSRD5A2PLAAT3PLAAT5 | |
| SCHEMBL7315746 | 0.90 | IGF1R (0.43) | FFAR1LTA4HSRD5A2PLAAT3PLAAT5 | |
| SCHEMBL19322269 | 0.90 | FFAR1 (0.60) | FFAR1LTA4HSRD5A2PLAAT3PLAAT5 | |
| SCHEMBL12040543 | 0.88 | FFAR1 (0.58) | FFAR1LTA4HSRD5A2PLAAT3PLAAT5 | |
| SCHEMBL19322272 | 0.88 | FFAR1 (0.62) | FFAR1LTA4HSRD5A2PLAAT3PLAAT5 | |
| SCHEMBL7456192 | 0.84 | TDP1 (0.62) | FFAR1LTA4HSRD5A2PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625981-A1 | AZABICYCLO COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993015080-A1 | AZABICYCLO COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | disclosed |