Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453691 | 0.93 | FFAR1 (0.42) | IGF1RALOX15FFAR1ST14SRD5A2 | |
| SCHEMBL7369384 | 0.92 | FFAR1 (0.53) | FFAR1SRD5A2LTA4HPLAAT3PLAAT5 | |
| SCHEMBL7364825 | 0.90 | FFAR1 (0.51) | FFAR1SRD5A2LTA4HPLAAT3PLAAT5 | |
| SCHEMBL7442396 | 0.90 | FFAR1 (0.51) | FFAR1SRD5A2LTA4HPLAAT3PLAAT5 | |
| SCHEMBL5380612 | 0.85 | FFAR1 (0.55) | FFAR1SRD5A2LTA4HPLAAT3PLAAT5 | |
| SCHEMBL2177163 | 0.85 | THRA (0.47) | IGF1RALOX15THRATHRB | |
| SCHEMBL22228113 | 0.84 | PARP10 (0.46) | FFAR1SRD5A2THRATHRB | |
| SCHEMBL6054583 | 0.83 | TDP1 (0.52) | FFAR1ST14SRD5A2LTA4H | |
| SCHEMBL9670640 | 0.83 | THRA (0.50) | THRATHRB | |
| SCHEMBL9673266 | 0.83 | THRA (0.50) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962513-A | CENTRAL NERVOUS SYSTEM, PSYCHOLOGICAL DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-05 | — | — | US | disclosed |
| US-5468882-A | Serotoninergic agents; central nervous system and psychological disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-21 | — | — | US | disclosed |
| US-5318988-A | Treating psychoses | BAYER AKTIENGESELLSCHAFT (DE) | 1994-06-07 | — | — | US | disclosed |