Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.64 |
| ▸ | ITGAV | P06756 | 6/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441813 | 0.88 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| SCHEMBL7441820 | 0.88 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| SCHEMBL7395210 | 0.88 | ITGB3 (0.65) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677554 | 0.88 | ITGB3 (0.70) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677549 | 0.88 | ITGB3 (0.70) | ITGB3ITGA2BITGAV | |
| SCHEMBL7338314 | 0.88 | ITGB3 (0.52) | ITGB3ITGA2BITGAV | |
| SCHEMBL7395216 | 0.88 | ITGB3 (0.65) | ITGB3ITGA2BITGAV | |
| SCHEMBL6947990 | 0.87 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL6951743 | 0.87 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| SCHEMBL6674672 | 0.87 | ITGB3 (0.71) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5977101-A | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5736540-A | CONGESTIVE HEART FAILURE | AMERICAN CYANAMID COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |