Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS11D | O60235 | 10/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 4/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | PLG | P00747 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770769 | 0.92 | TMPRSS11D (0.51) | TMPRSS11DCYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL7358827 | 0.91 | TMPRSS11D (0.52) | TMPRSS11DCYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL15252029 | 0.86 | TMPRSS11D (0.59) | TMPRSS11DCYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL15366489 | 0.86 | TMPRSS11D (0.59) | TMPRSS11DCYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL15251950 | 0.84 | TMPRSS11D (0.48) | TMPRSS11DCYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL15251832 | 0.84 | TMPRSS11D (0.48) | TMPRSS11DCYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL15366284 | 0.84 | TMPRSS11D (0.48) | TMPRSS11DCYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL8770799 | 0.84 | F10 (0.55) | TMPRSS11DF2F10TACR1 | |
| SCHEMBL7706395 | 0.83 | ALDH1A1 (0.55) | TMPRSS11DCYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL6783676 | 0.83 | TMPRSS11D (0.46) | TMPRSS11DF2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796271-B1 | DIPEPTIDE P-AMIDINOBENZYLAMIDES WITH N-TERMINAL SULFONYL OR AMINOSULFONYL RADICALS | BASF AG (DE) | 2000-02-02 | — | — | EP | disclosed |
| EP-0796271-A1 | NEW DIPEPTIDE P-AMIDINOBENZYLAMIDES WITH N-TERMINAL SULFONYL OR AMINOSULFONYL RADICALS | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996017860-A1 | NEW DIPEPTIDE P-AMIDINOBENZYLAMIDES WITH N-TERMINAL SULFONYL OR AMINOSULFONYL RADICALS | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |