SCHEMBL7365318

SCHEMBL7365318

C=CCCCCc1ccc(F)cc1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.45
SMN1; SMN2 Q16637 1/20 0.43
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HDAC1 Q13547 2/20 0.41
HDAC4 P56524 1/20 0.41
MAOB P27338 1/20 0.39
CYP19A1 P11511 1/20 0.39
AOC3 Q16853 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8072476 0.98 USP2 (0.44) TAAR1SMN1; SMN2USP2ALDH1A1HPGD
SCHEMBL8073020 0.98 USP2 (0.44) TAAR1SMN1; SMN2USP2ALDH1A1HPGD
SCHEMBL8072561 0.98 USP2 (0.44) TAAR1SMN1; SMN2USP2ALDH1A1HPGD
SCHEMBL8077499 0.98 USP2 (0.44) TAAR1SMN1; SMN2USP2ALDH1A1HPGD
SCHEMBL14027703 0.94 MAOB (0.48) TAAR1SMN1; SMN2USP2ALDH1A1HPGD
SCHEMBL8063276 0.94 TAAR1 (0.46) TAAR1SMN1; SMN2HDAC1HDAC4MAOB
SCHEMBL11328438 0.89 TDP1 (0.48) USP2ALDH1A1HPGDTDP1HDAC1
SCHEMBL14027699 0.88 MAOB (0.50) TAAR1SMN1; SMN2ALDH1A1HPGDHDAC1
SCHEMBL11336193 0.87 TDP1 (0.52) USP2ALDH1A1HPGDTDP1HDAC1
SCHEMBL12989712 0.87 TDP1 (0.52) USP2ALDH1A1HPGDTDP1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797881-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same Bio-Pharm Solutions Co., Ltd. (KR) 2014-11-05 EP disclosed
WO-2013100566-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed
US-6063940-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-05-16 US disclosed
US-5637736-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-10 US disclosed
EP-0672031-A1 CATECHOL DIETHERS AS SELECTIVE PDE IV? INHIBITORS PFIZER INC. (US) 1995-09-20 EP disclosed
EP-0637580-A1 Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-02-08 EP disclosed
WO-1994012461-A1 CATECHOL DIETHERS AS SELECTIVE PDEIV INHIBITORS PFIZER INC. (US) 1994-06-09 WO disclosed