Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.53 |
| ▸ | F2 | P00734 | 14/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7453858 | 0.94 | F10 (0.47) | F10F2PRSS1CA1CA2 | |
| Hydrochloric Acid SCHEMBL7361312 | 0.92 | F10 (0.54) | F10F2PRSS1CA1CA2 | |
| SCHEMBL7361417 | 0.90 | F10 (0.52) | F10F2PRSS1CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL7451183 | 0.87 | F10 (0.41) | F10F2PRSS1CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL7454348 | 0.84 | F10 (0.47) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7455028 | 0.84 | F10 (0.45) | F10F2PRSS1CA1CA2 | |
| SCHEMBL7363398 | 0.83 | F10 (0.58) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7451765 | 0.82 | F10 (0.45) | F10F2PRSS1CA1CA2 | |
| SCHEMBL7366768 | 0.81 | F10 (0.52) | F10F2PRSS1 | |
| SCHEMBL7367192 | 0.80 | F10 (0.42) | F10F2PRSS1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |