Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.58 |
| ▸ | F2 | P00734 | 2/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.51 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7458607 | 0.95 | F10 (0.53) | F10F2PRSS1HDAC8HTR6 | |
| SCHEMBL7361417 | 0.84 | F10 (0.52) | F10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7361312 | 0.84 | F10 (0.54) | F10F2PRSS1 | |
| SCHEMBL7365693 | 0.83 | F10 (0.53) | F10F2PRSS1 | |
| SCHEMBL7363395 | 0.82 | F10 (0.83) | F10F2PRSS1HDAC8HTR6 | |
| Trifluoroacetic Acid SCHEMBL7451765 | 0.80 | F10 (0.45) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7454348 | 0.79 | F10 (0.47) | F10F2PRSS1 | |
| SCHEMBL7367192 | 0.79 | F10 (0.42) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7453858 | 0.78 | F10 (0.47) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7458596 | 0.78 | F2 (0.75) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |