Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365758 | 1.00 | PPARA (0.42) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7370786 | 0.89 | MRGPRX4 (0.44) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7370784 | 0.89 | MRGPRX4 (0.44) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7365379 | 0.87 | LMNA (0.41) | PPARAPPARGPPARDKCNQ3KCNQ2 | |
| SCHEMBL7365381 | 0.87 | LMNA (0.41) | PPARAPPARGPPARDKCNQ3KCNQ2 | |
| SCHEMBL7367034 | 0.85 | PPARA (0.44) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7360754 | 0.77 | PPARA (0.49) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6940168 | 0.77 | MAPT (0.46) | — | |
| SCHEMBL6940165 | 0.77 | MAPT (0.46) | — | |
| SCHEMBL6940097 | 0.77 | LMNA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |