Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365900 | 1.00 | USP2 (0.53) | USP2NPC1RAB9ACDK5CDK5R1 | |
| Trifluoroacetic Acid SCHEMBL7285829 | 0.91 | USP2 (0.46) | USP2NPC1RAB9ACDK5CDK5R1 | |
| Trifluoroacetic Acid SCHEMBL7285822 | 0.91 | USP2 (0.46) | USP2NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL7287083 | 0.80 | KMT2A (0.43) | NPC1RAB9AF2PRSS1PRSS2 | |
| SCHEMBL7284589 | 0.79 | TNF (0.50) | USP2NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL7285835 | 0.77 | SMN1; SMN2 (0.47) | USP2NPC1RAB9ACDK5CDK5R1 | |
| Trifluoroacetic Acid SCHEMBL8383199 | 0.75 | NPC1 (0.43) | USP2NPC1RAB9ACDK5CDK5R1 | |
| Trifluoroacetic Acid SCHEMBL7281971 | 0.75 | NPC1 (0.43) | USP2NPC1RAB9ACDK5CDK5R1 | |
| Paraben SCHEMBL28117002 | 0.71 | CA2 (0.70) | HPGDSMN1; SMN2CA1CA2MAPT | |
| Terephthalic Acid SCHEMBL11164993 | 0.71 | TSHR (0.75) | HPGDSMN1; SMN2CA1CA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822931-A1 | PIPERAZINONES USEFUL AS INHIBITORS OF PLATELET AGGREGATION | Takeda Chemical Industries, Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033982-A1 | PIPERAZINONES USEFUL AS INHIBITORS OF PLATELET AGGREGATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |