Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 11/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 10/20 | 0.44 |
| ▸ | HTR7 | P34969 | 4/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366540 | 0.94 | DRD2 (0.50) | HTR6DRD2SLC6A4ACHEHTR2A | |
| SCHEMBL7360762 | 0.91 | DRD2 (0.51) | HTR6DRD2SLC6A4ACHEHTR2A | |
| SCHEMBL7368300 | 0.87 | DRD2 (0.50) | HTR6DRD2SLC6A4ACHEHTR2A | |
| SCHEMBL7364405 | 0.86 | DRD2 (0.49) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL7360772 | 0.85 | DRD2 (0.53) | DRD2SLC6A4ACHEHTR2AHTR2C | |
| SCHEMBL7370354 | 0.82 | DRD2 (0.52) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL7365738 | 0.81 | DRD2 (0.51) | DRD2SLC6A4ACHEHTR2AHTR2C | |
| SCHEMBL7368733 | 0.80 | DRD2 (0.53) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL7365706 | 0.80 | DRD2 (0.55) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL7367433 | 0.80 | DRD2 (0.55) | DRD2SLC6A4ACHEHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780474-A | ADMINISTERING IN THE TREATMENT OF PSYCHOTIC DISORDERS, ANXIO-DEPRESSIVE DISORDERS AND AGGRESSIVENESS | ADIR ET COMPAGNIE (FR) | 1998-07-14 | — | — | US | disclosed |