Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10590747 | 0.85 | SLC6A2 (0.42) | TAAR1F2PRSS1ALDH1A1HPGD | |
| SCHEMBL4975451 | 0.72 | TAAR1 (0.42) | TAAR1F2PRSS1RAB9ATSHR | |
| SCHEMBL7452644 | 0.71 | TAAR1 (0.53) | TAAR1ALDH1A1GLARAB9APOLB | |
| SCHEMBL7452648 | 0.71 | TAAR1 (0.53) | TAAR1ALDH1A1GLARAB9APOLB | |
| SCHEMBL7230439 | 0.71 | TAAR1 (0.53) | TAAR1ALDH1A1GLARAB9APOLB | |
| SCHEMBL5194706 | 0.69 | TLR9 (0.46) | GAA | |
| SCHEMBL3684121 | 0.69 | TLR9 (0.46) | GAA | |
| SCHEMBL5194710 | 0.69 | TLR9 (0.46) | GAA | |
| SCHEMBL5194716 | 0.69 | TLR9 (0.46) | GAA | |
| SCHEMBL4384032 | 0.68 | TAAR1 (0.53) | TAAR1ALDH1A1HPGDUSP2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |