Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5194710 | 1.00 | TLR9 (0.46) | TLR9CES2CES1AKR1B1CTRB1 | |
| SCHEMBL5194716 | 1.00 | TLR9 (0.46) | TLR9CES2CES1AKR1B1CTRB1 | |
| SCHEMBL5194706 | 1.00 | TLR9 (0.46) | TLR9CES2CES1AKR1B1CTRB1 | |
| SCHEMBL6069576 | 0.81 | FASN (0.47) | FASNKEAP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6817041 | 0.81 | FASN (0.47) | FASNKEAP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6069567 | 0.81 | FASN (0.47) | FASNKEAP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4604644 | 0.81 | FASN (0.47) | FASNKEAP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9692649 | 0.80 | BACE1 (0.52) | TLR9BACE1MEN1KMT2A | |
| SCHEMBL8056399 | 0.79 | TLR9 (0.51) | TLR9LTB4RLTB4R2HTTKMT2A | |
| SCHEMBL18175957 | 0.78 | CTRB1 (0.42) | TLR9CES2CES1AKR1B1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834190-B2 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof | KANEKA CORPORATION (JP) | 2010-11-16 | — | — | US | disclosed |
| US-7834190-B2 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof | KANEKA CORPORATION (JP) | 2010-11-16 | — | — | US | disclosed |
| US-7834190-B2 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof | KANEKA CORPORATION (JP) | 2010-11-16 | — | — | US | disclosed |
| US-20100048909-A1 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof | KANEKA CORPORATION | 2010-02-25 | — | — | US | disclosed |
| US-20100048909-A1 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof | KANEKA CORPORATION | 2010-02-25 | — | — | US | disclosed |
| US-20100048909-A1 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof | KANEKA CORPORATION | 2010-02-25 | — | — | US | disclosed |
| EP-2039689-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-2 -HYDROXYPROPIONIC CYCLOPROPYLAMIDE DERIVATIVES AND SALTS THEREOF | Kaneka Corporation (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-2039689-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-2 -HYDROXYPROPIONIC CYCLOPROPYLAMIDE DERIVATIVES AND SALTS THEREOF | Kaneka Corporation (JP) | 2009-03-25 | — | — | EP | disclosed |
| US-5581007-A | Process for preparing optically active allophenylnorstatin derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0729939-A2 | Process for preparing optically active allophenylnorstatin derivatives, and intermediates for use therein | Takasago International Corporation (JP) | 1996-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048909-A1 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof | HPD, HAAO, OGFOD1 | TLR9 4328/4885CES2 316/4885CES1 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.