SCHEMBL7366359

SCHEMBL7366359

NCC(=O)N(CC(=O)O)C(=O)C(N)Cc1ccc(O)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.54
YARS1 P54577 2/20 0.41
HDAC8 Q9BY41 2/20 0.40
TAAR1 Q96RJ0 3/20 0.39
SLC6A2 P23975 1/20 0.39
ERAP2 Q6P179 1/20 0.38
LNPEP Q9UIQ6 1/20 0.38
ALPI P09923 1/20 0.38
PKM P14618 1/20 0.38
PTGS1 P23219 1/20 0.38
XIAP P98170 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
CA2 P00918 1/20 0.38
CAMK2A Q9UQM7 1/20 0.38
OPRD1 P41143 1/20 0.37
DPP4 P27487 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27343864 1.00 SLC7A5 (0.54) SLC7A5YARS1HDAC8TAAR1SLC6A2
SCHEMBL7587110 0.89 ALPI (0.51) SLC7A5HDAC8ALPIPKMPTGS1
SCHEMBL27426539 0.89 ALPI (0.51) SLC7A5HDAC8ALPIPKMPTGS1
SCHEMBL8673016 0.86 SLC7A5 (0.57) SLC7A5YARS1HDAC8TAAR1SLC6A2
SCHEMBL9724064 0.86 SLC7A5 (0.57) SLC7A5YARS1HDAC8TAAR1SLC6A2
SCHEMBL27375801 0.86 SLC7A5 (0.57) SLC7A5YARS1HDAC8TAAR1SLC6A2
SCHEMBL30440024 0.78 SLC7A5 (0.58) SLC7A5YARS1HDAC8TAAR1SLC6A2
SCHEMBL7588100 0.77 SLC7A5 (0.56) SLC7A5YARS1HDAC8TAAR1SLC6A2
SCHEMBL28794185 0.77 SLC7A5 (0.56) SLC7A5YARS1HDAC8TAAR1SLC6A2
SCHEMBL28794174 0.77 SLC7A5 (0.56) SLC7A5YARS1HDAC8TAAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0597838-B1 VACCINE COMPOSITIONS NORTH AMERICAN VACCINE INC (CA) 1998-12-02 EP claimed
EP-0549617-B1 IMPROVED VACCINE COMPOSITIONS NORTH AMERICAN VACCINE INC (CA) 1996-03-27 EP claimed
EP-0597838-A1 VACCINE COMPOSITIONS NORTH AMERICAN VACCINE, INC. (CA) 1994-05-25 EP claimed
EP-0549617-A1 IMPROVED VACCINE COMPOSITIONS. NORTH AMERICAN VACCINE INC (CA) 1993-07-07 EP claimed
CN-1060408-A Improved vaccine combination NORTH AMERICAN VACCINE INC (CA) 1992-04-22 CN claimed
WO-1992004915-A1 IMPROVED VACCINE COMPOSITIONS NORTH AMERICAN VACCINE, INC. (CA) 1992-04-02 WO claimed
CN-1056816-A The vaccine combination of improvement NORTH AMERICAN VACCINES INC (CA) 1991-12-11 CN claimed
WO-1991016926-A1 VACCINE COMPOSITIONS NORTH AMERICAN VACCINE, INC. (CA) 1991-11-14 WO claimed
CN-100333787-C YG and YGG for use as medicaments for maintaining and improving immune response GAUTRIBE M (US) 2007-08-29 CN disclosed
CN-1644214-A YG and YGG for use as medicaments for maintaining and improving immune response GAUTRIBE M (US) 2005-07-27 CN disclosed
US-6156555-A Method of preparing an enzyme participating in C-terminal amidation SHISEIDO COMPANY LTD. (JP) 2000-12-05 US disclosed
EP-0666318-B1 Enzyme participating in c-terminal amidation, and method of preparing same and use thereof SHISEIDO CO LTD (JP) 2000-11-29 EP disclosed
US-5871995-A Purified enzymes participating in C-terminal amidation SHISEIDO COMPANY, LTD. (JP) 1999-02-16 US disclosed
EP-0884389-A1 Enzyme participating in C-terminal amidation, and method of preparing same and use thereof SHISEIDO COMPANY LIMITED (JP) 1998-12-16 EP disclosed
EP-0103077-B1 SUBSTITUTED DIPEPTIDES, METHODS FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, METHOD FOR MAKING SUCH PHARMACEUTICAL COMPOSITIONS SCHERING CORPORATION (US) 1988-05-18 EP disclosed
US-4721726-A ANALGESICS SCHERING CORPORATION (US) 1988-01-26 US disclosed
EP-0117429-B1 PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES SCHERING CORPORATION (US) 1987-09-02 EP disclosed
US-4610816-A ANALGESICS SCHERING CORPORATION (US) 1986-09-09 US disclosed
EP-0117429-A1 Phosphorous containing compounds as inhibitors of enkephalinases SCHERING CORPORATION (US) 1984-09-05 EP disclosed
EP-0103077-A2 Substituted dipeptides, methods for their production, pharmaceutical compositions containing them, method for making such pharmaceutical compositions SCHERING CORPORATION (US) 1984-03-21 EP disclosed