SCHEMBL7587110

SCHEMBL7587110

NCC(=O)N(CC(=O)O)C(=O)C(N)Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.51
PKM P14618 1/20 0.51
PTGS1 P23219 1/20 0.51
XIAP P98170 1/20 0.51
SLC7A5 Q01650 1/20 0.51
SLC15A1 P46059 1/20 0.49
LTA4H P09960 1/20 0.47
SLC1A3 P43003 2/20 0.45
SLC1A2 P43004 2/20 0.45
SLC1A1 P43005 2/20 0.45
MC4R P32245 2/20 0.43
MC5R P33032 1/20 0.43
MC3R P41968 1/20 0.43
MMP2 P08253 1/20 0.42
CYP1A2 P05177 1/20 0.42
CPA1 P15085 2/20 0.41
CPA3 P15088 2/20 0.41
CPB1 P15086 1/20 0.41
CPB2 Q96IY4 1/20 0.41
HDAC8 Q9BY41 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27426539 1.00 ALPI (0.51) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27343864 0.89 SLC7A5 (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7366359 0.89 SLC7A5 (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL29027552 0.86 MMP2 (0.51) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL14691646 0.85 ALPI (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL8005620 0.85 ALPI (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL28540563 0.83 ALPI (0.46) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL22229861 0.81 ANPEP (0.57) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL22229863 0.81 ANPEP (0.57) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL29250275 0.80 SLC7A5 (0.40) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108976976-A A kind of environment protecting water-based paint and preparation method thereof 宁波帝杨电子科技有限公司 2018-12-11 CN claimed
CN-108178266-A A kind of efficient sewage treatment flocculant and preparation method thereof 王欣欣 2018-06-19 CN claimed
CN-102300870-B Low molecular weight polysulfated hyaluronic acid derivatives and medicines containing the same OTSUKA CHEMICAL CO LTD 2014-12-03 CN claimed
CN-108645804-A A kind of reagent for testing angiotonin converzyme box 金华市强盛生物科技有限公司 2018-10-12 CN disclosed
CN-108178266-A A kind of efficient sewage treatment flocculant and preparation method thereof 王欣欣 2018-06-19 CN disclosed
CN-102300870-B Low molecular weight polysulfated hyaluronic acid derivatives and medicines containing the same OTSUKA CHEMICAL CO LTD 2014-12-03 CN disclosed
CN-102300870-A Low molecular weight polysulfated hyaluronic acid derivatives and medicines containing the same 2011-12-28 CN disclosed
CN-1693878-A Method and kit for scaling investigating angiotensin aminopherase ZHEJIANG YAKE PHARMACEUTICAL C (CN) 2005-11-09 CN disclosed
CN-1127513-C Phosphonic acid derivatives with metallopeptidase inhibitory activity ZAMBON SPA (IT) 2003-11-12 CN disclosed
EP-0438600-B2 ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF SHISEIDO CO LTD (JP) 2002-10-09 EP disclosed
US-6156555-A Method of preparing an enzyme participating in C-terminal amidation SHISEIDO COMPANY LTD. (JP) 2000-12-05 US disclosed
US-5871995-A Purified enzymes participating in C-terminal amidation SHISEIDO COMPANY, LTD. (JP) 1999-02-16 US disclosed
CN-1202901-A Phosphonic acid derivatives with metallopeptidase inhibitory activity ZAMBON SPA (IT) 1998-12-23 CN disclosed
EP-0884389-A1 Enzyme participating in C-terminal amidation, and method of preparing same and use thereof SHISEIDO COMPANY LIMITED (JP) 1998-12-16 EP disclosed
EP-0438600-B1 ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF SHISEIDO CO LTD (JP) 1996-02-07 EP disclosed
EP-0666318-A1 Enzyme participating in c-terminal amidation, and method of preparing same and use thereof SHISEIDO COMPANY LIMITED (JP) 1995-08-09 EP disclosed
US-5354675-A Amidation of glycine SHISEIDO COMPANY LTD. (JP) 1994-10-11 US disclosed
EP-0447547-B1 C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE SHISEIDO CO LTD (JP) 1994-07-27 EP disclosed
EP-0447547-A1 C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE SHISEIDO COMPANY LIMITED (JP) 1991-09-25 EP disclosed
EP-0438600-A1 ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF SHISEIDO COMPANY LIMITED (JP) 1991-07-31 EP disclosed