Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114396 | 1.00 | KMT2A (0.57) | KMT2AMAPTPAOXCES2CES1 | |
| SCHEMBL115642 | 1.00 | KMT2A (0.57) | KMT2AMAPTPAOXCES2CES1 | |
| SCHEMBL115465 | 1.00 | KMT2A (0.57) | KMT2AMAPTPAOXCES2CES1 | |
| SCHEMBL28339497 | 0.92 | KMT2A (0.57) | KMT2AMAPTCES2CES1FAAH | |
| SCHEMBL118316 | 0.89 | KMT2A (0.59) | KMT2AMAPTCES2CES1FAAH | |
| SCHEMBL116778 | 0.89 | KMT2A (0.59) | KMT2AMAPTCES2CES1FAAH | |
| SCHEMBL738677 | 0.89 | KMT2A (0.59) | KMT2AMAPTCES2CES1FAAH | |
| SCHEMBL114957 | 0.89 | KMT2A (0.59) | KMT2AMAPTCES2CES1FAAH | |
| SCHEMBL1147864 | 0.89 | PAOX (0.47) | KMT2AMAPTPAOXALDH1A1 | |
| SCHEMBL115551 | 0.88 | KMT2A (0.57) | KMT2AMAPTCES2CES1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658508-B2 | TWO-PART HAIR COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2024-06-19 | — | — | EP | disclosed |
| EP-2658508-B1 | TWO-PART HAIR COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2021-06-16 | — | — | EP | disclosed |
| EP-2560606-B1 | COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| EP-2560608-B1 | COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2017-04-05 | — | — | EP | disclosed |
| EP-2346481-B1 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KAO GERMANY GMBH (DE) | 2016-08-31 | — | — | EP | disclosed |
| EP-2377513-B1 | Colouring composition | KAO GERMANY GMBH (DE) | 2016-03-30 | — | — | EP | disclosed |
| EP-2346480-B1 | COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2016-01-06 | — | — | EP | disclosed |
| US-8795391-B2 | Colouring composition | KAO GERMANY GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-8673022-B2 | Colouring composition | KAO GERMANY GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8668746-B2 | Two-part hair colouring composition | KAO GERMANY GMBH (DE) | 2014-03-11 | — | — | US | disclosed |
| EP-2377511-A1 | Colouring composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2011-10-19 | — | — | EP | disclosed |
| EP-2377513-A1 | Colouring composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20110240052-A1 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH | 2011-10-06 | — | — | US | disclosed |
| US-20110197912-A1 | COLORING COMPOSITION | KPSS-KAO PROFESSIONAL SAL SERVICES GMBH | 2011-08-18 | — | — | US | disclosed |
| EP-2346481-A2 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KPSS-Kao Professional Salon Services GmbH (DE) | 2011-07-27 | — | — | EP | disclosed |
| EP-2346480-A2 | COLOURING COMPOSITION | KPSS-Kao Professional Salon Services GmbH (DE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010046077-A2 | COLOURING COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046080-A2 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| EP-2177204-A1 | Colouring composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
| EP-2177205-A1 | Composition for the permanent shaping of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110197912-A1 | COLORING COMPOSITION | KRT18, POLL, POLQ | KMT2A 758/4885MAPT 176/4885PAOX 2196/4885 |
| US-20110240052-A1 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | POLR1C, DRD3, DRD4 | KMT2A 1457/4885MAPT 3299/4885PAOX 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.