Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370572 | 0.95 | MAPT (0.46) | HDAC1HDAC2MAPTRXFP1ALOX5 | |
| SCHEMBL7372051 | 0.93 | HDAC1 (0.39) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL7376615 | 0.84 | EPHX2 (0.39) | EPHX2 | |
| SCHEMBL10585926 | 0.83 | L3MBTL1 (0.45) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL7374066 | 0.82 | S1PR3 (0.40) | SMN1; SMN2NPC1RAB9ATDP1MAPT | |
| SCHEMBL7323963 | 0.81 | GAA (0.46) | NPC1RAB9AEPHX2TSHRHPGD | |
| SCHEMBL7372921 | 0.79 | SMN1; SMN2 (0.46) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL7374941 | 0.79 | PREP (0.41) | MAPK1SMN1; SMN2SLC6A3NPC1RAB9A | |
| SCHEMBL7375337 | 0.78 | HDAC1 (0.42) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL7372636 | 0.78 | DPP4 (0.36) | SMN1; SMN2NPC1TDP1EPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461677-B1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | claimed |
| EP-0461677-A1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |
| EP-0799224-A1 | NOVEL QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-08 | — | — | EP | disclosed |